Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19674641 | 0.91 | PIK3CD (0.47) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL5271932 | 0.89 | HPGD (0.53) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL19768828 | 0.86 | HPGD (0.50) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL4106700 | 0.84 | EPHX1 (0.50) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL4101370 | 0.84 | EPHX1 (0.50) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL609639 | 0.84 | EPHX1 (0.50) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL18015125 | 0.84 | HPGD (0.51) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL21997569 | 0.83 | HPGD (0.48) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL21997256 | 0.83 | HPGD (0.48) | RECQLUSP2SMN1; SMN2HPGDEPHX1 | |
| SCHEMBL21997254 | 0.83 | HPGD (0.48) | RECQLUSP2SMN1; SMN2HPGDEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673247-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS. | MERCK & CO INC (US) | 1996-05-01 | — | — | EP | disclosed |
| EP-0673247-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1995-09-27 | — | — | EP | disclosed |