Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20612872 | 0.84 | ACE2 (0.64) | LTA4HCYP1A2ACE2BLMGABRR1 | |
| SCHEMBL5977939 | 0.84 | ACE2 (0.64) | LTA4HCYP1A2ACE2BLMGABRR1 | |
| SCHEMBL31073666 | 0.84 | ACE2 (0.64) | LTA4HCYP1A2ACE2BLMGABRR1 | |
| SCHEMBL9001608 | 0.84 | ACE2 (0.64) | LTA4HCYP1A2ACE2BLMGABRR1 | |
| SCHEMBL2763157 | 0.83 | CYP1A2 (0.67) | LTA4HCYP1A2ACE2BLMFFAR4 | |
| SCHEMBL22190484 | 0.83 | LTA4H (0.62) | LTA4HCYP1A2ACE2BLMGABRR1 | |
| SCHEMBL2835395 | 0.83 | CYP1A2 (0.67) | LTA4HCYP1A2ACE2BLMFFAR4 | |
| SCHEMBL21998 | 0.83 | CYP1A2 (0.67) | LTA4HCYP1A2ACE2BLMFFAR4 | |
| SCHEMBL3816098 | 0.83 | CYP1A2 (0.67) | LTA4HCYP1A2ACE2BLMFFAR4 | |
| SCHEMBL3811423 | 0.83 | CYP1A2 (0.67) | LTA4HCYP1A2ACE2BLMFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712405-A1 | DERIVATIVES OF MONIC ACIDS A AND C HAVING ANTIBACTERIAL, ANTIMYCOPLASMATICAL, ANTIFUNGAL AND HERBICIDAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995005384-A1 | DERIVATIVES OF MONIC ACIDS A AND C HAVING ANTIBACTERIAL, ANTIMYCOPLASMATICAL, ANTIFUNGAL AND HERBICIDAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1995-02-23 | — | — | WO | disclosed |