Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9431922 | 0.90 | MEN1 (0.53) | CYP1A2PDE10AALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL9032897 | 0.86 | FFAR1 (0.54) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL9034329 | 0.85 | FFAR1 (0.53) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL9034967 | 0.85 | FFAR1 (0.55) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL1558239 | 0.85 | FFAR1 (0.55) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL9031804 | 0.85 | FFAR1 (0.55) | FFAR1AKR1B1PDE10AALOX5CYSLTR1 | |
| SCHEMBL22209200 | 0.84 | FFAR1 (0.55) | FFAR1AKR1B1CYP1A2PDE10AALOX5 | |
| SCHEMBL9033868 | 0.84 | FFAR1 (0.54) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL9430514 | 0.82 | FFAR1 (0.52) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL9430772 | 0.82 | FFAR1 (0.52) | FFAR1AKR1B1ALOX5CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499926-B1 | 2-Substituted quinolines, process for their preparation as well as their use in medicaments | BAYER AG (DE) | 1996-09-11 | — | — | EP | disclosed |
| US-5304563-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-19 | — | — | US | disclosed |