Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.52 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584268 | 0.94 | FFAR1 (0.60) | FFAR1AKR1B1CYSLTR1CYSLTR2PPARG | |
| SCHEMBL9581742 | 0.89 | FFAR1 (0.68) | FFAR1AKR1B1CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL9430587 | 0.88 | ALOX5 (0.50) | CYSLTR1PDE10APPARGALOX5 | |
| SCHEMBL9034967 | 0.86 | FFAR1 (0.55) | FFAR1AKR1B1CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL1558239 | 0.86 | FFAR1 (0.55) | FFAR1AKR1B1CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9430772 | 0.85 | FFAR1 (0.52) | FFAR1AKR1B1CYSLTR1CYSLTR2PPARG | |
| SCHEMBL9032897 | 0.85 | FFAR1 (0.54) | FFAR1AKR1B1CYSLTR1CYSLTR2PPARG | |
| SCHEMBL9033146 | 0.85 | FFAR1 (0.54) | FFAR1AKR1B1CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL3271474 | 0.84 | GPBAR1 (0.67) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5 | |
| SCHEMBL9034329 | 0.84 | FFAR1 (0.53) | FFAR1AKR1B1CYSLTR1CYSLTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499926-B1 | 2-Substituted quinolines, process for their preparation as well as their use in medicaments | BAYER AG (DE) | 1996-09-11 | — | — | EP | disclosed |
| US-5304563-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-19 | — | — | US | disclosed |
| EP-0499926-A1 | 2-Substituted quinolines, process for their preparation as well as their use in medicaments | BAYER AG (DE) | 1992-08-26 | — | — | EP | disclosed |