Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 2/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | LDHB | P07195 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4956215 | 1.00 | SLC7A5 (0.46) | SLC7A5TP53ECE1SLC1A3SLC1A2 | |
| SCHEMBL7632543 | 1.00 | SLC7A5 (0.46) | SLC7A5TP53ECE1SLC1A3SLC1A2 | |
| SCHEMBL9032536 | 0.84 | SLC7A5 (0.38) | SLC7A5TP53ECE1ACHELMNA | |
| SCHEMBL593998 | 0.81 | TP53 (0.50) | SLC7A5TP53ECE1SLC1A3SLC1A2 | |
| SCHEMBL30775137 | 0.81 | ACHE (0.43) | SLC7A5TP53ACHELMNAALOX15 | |
| SCHEMBL6897235 | 0.78 | SLC7A5 (0.42) | SLC7A5TP53ECE1SLC1A3SLC1A2 | |
| SCHEMBL21268828 | 0.78 | TP53 (0.47) | SLC7A5TP53ECE1SLC1A3SLC1A2 | |
| SCHEMBL21269919 | 0.78 | TP53 (0.47) | SLC7A5TP53ECE1SLC1A3SLC1A2 | |
| SCHEMBL21269742 | 0.78 | TP53 (0.47) | SLC7A5TP53ECE1SLC1A3SLC1A2 | |
| SCHEMBL28314358 | 0.78 | TP53 (0.47) | SLC7A5TP53ECE1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444482-B1 | Oxetanones | HOFFMANN LA ROCHE (CH) | 1996-01-17 | — | — | EP | disclosed |
| EP-0444482-A2 | Oxetanones | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-04 | — | — | EP | disclosed |