Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034666 | 0.86 | LMNA (0.60) | LMNAKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL27350251 | 0.83 | LMNA (0.51) | LMNAKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL9032918 | 0.82 | LMNA (0.56) | LMNAKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL9034060 | 0.82 | LMNA (0.56) | LMNAKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL6394425 | 0.82 | LMNA (0.50) | LMNAKMT2AGAAMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9400437 | 0.81 | LMNA (0.55) | LMNAKMT2AGAAMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9400521 | 0.81 | LMNA (0.55) | LMNAKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL9400533 | 0.80 | LMNA (0.53) | LMNAKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL9034367 | 0.80 | LMNA (0.53) | LMNAKMT2AGAAMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9034371 | 0.79 | LMNA (0.52) | LMNAKMT2AGAAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442348-B1 | Imidazole compounds, process for preparation, medicaments based on these compounds and some intermediates | HOECHST AG (DE) | 1996-07-17 | — | — | EP | disclosed |
| US-5356922-A | Treatment of disturbances in microcirculation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-18 | — | — | US | disclosed |
| US-5232922-A | Cardiovascular disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-03 | — | — | US | disclosed |
| EP-0442348-A2 | Imidazole compounds, process for preparation, medicaments based on these compounds and some intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-21 | — | — | EP | disclosed |