Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CALML3 | P27482 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032610 | 0.84 | MAOA (0.55) | CHRNA7GRM2MAOBMAOADRD2 | |
| SCHEMBL2823684 | 0.81 | GRM2 (0.63) | GRM2 | |
| SCHEMBL9034428 | 0.80 | MAOA (0.58) | MAOBMAOACALML3 | |
| SCHEMBL16685547 | 0.73 | F10 (0.37) | GRM2MAOBMAOACALML3 | |
| SCHEMBL16685545 | 0.73 | F10 (0.37) | GRM2MAOBMAOACALML3 | |
| SCHEMBL8867483 | 0.73 | GRM2 (0.39) | CHRNA7GRM2MAOBMAOA | |
| SCHEMBL16686051 | 0.71 | F10 (0.37) | — | |
| SCHEMBL16686054 | 0.71 | F10 (0.37) | — | |
| SCHEMBL16685979 | 0.70 | MAOA (0.36) | GRM2MAOBMAOA | |
| SCHEMBL16685982 | 0.70 | MAOA (0.36) | GRM2MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0694544-A1 | Benzofuranyl- and benzothienyloxazolidinones | BAYER AG (DE) | 1996-01-31 | — | — | EP | disclosed |