Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032615 | 0.91 | BRD4 (0.38) | ITGB3ITGAVOXER1 | |
| SCHEMBL9465390 | 0.89 | OXER1 (0.38) | ITGB3ITGAVOXER1 | |
| SCHEMBL9465516 | 0.87 | KDM4E (0.33) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL9032728 | 0.86 | GRIN2D (0.36) | ITGB3ITGAVMAPT | |
| SCHEMBL9034483 | 0.85 | ITGB3 (0.37) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL9033646 | 0.85 | ITGB3 (0.43) | ITGB3ITGAVOXER1 | |
| SCHEMBL9034512 | 0.85 | ITGB3 (0.41) | ITGB3ITGAV | |
| SCHEMBL9034650 | 0.85 | GCGR (0.35) | ITGB3ITGAV | |
| SCHEMBL9033860 | 0.85 | ITGB3 (0.44) | ITGB3ITGAVOXER1 | |
| SCHEMBL9031376 | 0.84 | ITGB3 (0.40) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511477-B1 | Indole derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5239083-A | Anticarcinogenic agents, prostate cancer treatment | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| EP-0511477-A1 | Indole derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-11-04 | — | — | EP | disclosed |