Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032739 | 0.95 | ABCB1 (0.40) | ABCB1ANPEPKMT2AHDAC8GPR119 | |
| SCHEMBL9033588 | 0.94 | ABCB1 (0.40) | ABCB1ANPEPKMT2AHDAC8GPR119 | |
| SCHEMBL9035126 | 0.93 | ABCB1 (0.40) | ABCB1KMT2AHDAC8GPR119MEN1 | |
| SCHEMBL9033839 | 0.93 | KMT2A (0.40) | ABCB1KMT2ATSHR | |
| SCHEMBL9033882 | 0.92 | ABCB1 (0.42) | ABCB1KMT2AHDAC8GPR119MEN1 | |
| SCHEMBL9034508 | 0.91 | ABCB1 (0.39) | ABCB1KMT2AGPR119MEN1KLK7 | |
| SCHEMBL9034862 | 0.91 | ABCB1 (0.37) | ABCB1KMT2AGPR119MEN1KLK7 | |
| SCHEMBL9034739 | 0.90 | ABCB1 (0.41) | ABCB1KMT2AGPR119MEN1KLK7 | |
| SCHEMBL9034722 | 0.90 | ABCB1 (0.41) | ABCB1KMT2AGPR119MEN1KLK7 | |
| SCHEMBL9034729 | 0.90 | ABCB1 (0.41) | ABCB1KMT2AGPR119MEN1KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |