Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 5/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033847 | 0.95 | TACR1 (0.40) | KMT2ATACR1ABCB1CETPNPC1 | |
| SCHEMBL9033581 | 0.93 | ABCB1 (0.42) | KMT2AABCB1TSHR | |
| SCHEMBL9035126 | 0.92 | ABCB1 (0.40) | KMT2ATACR1ABCB1 | |
| SCHEMBL9032739 | 0.88 | ABCB1 (0.40) | KMT2AABCB1 | |
| SCHEMBL9033588 | 0.87 | ABCB1 (0.40) | KMT2ATACR1ABCB1 | |
| SCHEMBL9035133 | 0.87 | ABCB1 (0.39) | KMT2ATACR1ABCB1 | |
| SCHEMBL9033882 | 0.87 | ABCB1 (0.42) | KMT2AABCB1 | |
| SCHEMBL9034508 | 0.86 | ABCB1 (0.39) | KMT2ATACR1ABCB1 | |
| SCHEMBL9034862 | 0.85 | ABCB1 (0.37) | KMT2AABCB1 | |
| SCHEMBL9034732 | 0.85 | ABCB1 (0.41) | KMT2ATACR1ABCB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |