SCHEMBL9033628

SCHEMBL9033628

Cc1nc(CCCCl)c[nH]1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27716575 0.94 SMN1; SMN2 (0.34) SMN1; SMN2
SCHEMBL28626405 0.92 SMN1; SMN2 (0.33) SMN1; SMN2
Hydrochloric Acid SCHEMBL28339356 0.91 SMN1; SMN2 (0.36) SMN1; SMN2
SCHEMBL28113271 0.88
SCHEMBL30586310 0.87 SMN1; SMN2 (0.31) SMN1; SMN2
SCHEMBL1532157 0.82 NOS2 (0.43)
SCHEMBL7850217 0.80 KDM4E (0.33)
SCHEMBL29569302 0.80 NOS2 (0.42)
SCHEMBL7701413 0.80 KCNH2 (0.47)
SCHEMBL29569048 0.80 NOS2 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673247-A4 FIBRINOGEN RECEPTOR ANTAGONISTS. MERCK & CO INC (US) 1996-05-01 EP disclosed
EP-0673247-A1 FIBRINOGEN RECEPTOR ANTAGONISTS MERCK & CO. INC. (US) 1995-09-27 EP disclosed
EP-0510036-A1 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES. RHONE POULENC RORER SA (FR) 1992-10-28 EP disclosed
WO-1991010662-A1 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES RHONE-POULENC RORER S.A. (FR) 1991-07-25 WO disclosed