SCHEMBL9033727

SCHEMBL9033727

COC1C[N]CC1NCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 11/20 0.45
MAOA P21397 7/20 0.45
FUCA1 P04066 1/20 0.43
GAA P10253 1/20 0.41
MAOB P27338 6/20 0.41
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
GRIN2B Q13224 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9773716 0.78 KDM1A (0.45) KDM1AMAOAFUCA1GAAMAOB
SCHEMBL9773718 0.78 KDM1A (0.45) KDM1AMAOAFUCA1GAAMAOB
SCHEMBL6215374 0.78 KDM1A (0.45) KDM1AMAOAFUCA1GAAMAOB
SCHEMBL2095392 0.76 FUCA1 (0.50) KDM1AMAOAFUCA1MAOBGRIN2B
SCHEMBL2095964 0.76 FUCA1 (0.50) KDM1AMAOAFUCA1MAOBGRIN2B
SCHEMBL9760564 0.75 KDM4E (0.43) KDM1AMAOAFUCA1GAAMAOB
SCHEMBL9760561 0.75 KDM4E (0.43) KDM1AMAOAFUCA1GAAMAOB
SCHEMBL9760547 0.75 KDM4E (0.43) KDM1AMAOAFUCA1GAAMAOB
Hydrochloric Acid SCHEMBL9721902 0.73 KDM4E (0.41) KDM1AMAOAFUCA1GAAMAOB
Hydrochloric Acid SCHEMBL9721904 0.73 KDM4E (0.41) KDM1AMAOAFUCA1GAAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0470578-B1 Novel tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same WAKUNAGA SEIYAKU KK (JP) 1996-11-06 EP disclosed
EP-0700912-A1 QUINOLONE DERIVATIVE OR SALT THEREOF, AND ANTIBACTERIAL CONTAINING THE SAME WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1996-03-13 EP disclosed
US-5412098-A Quinolone derivative or salt thereof and antibacterial containing the same WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1995-05-02 US disclosed
US-5407932-A Bactericides WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1995-04-18 US disclosed
US-5399553-A Oral absorbability WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1995-03-21 US disclosed
EP-0393400-B1 Novel quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same WAKUNAGA SEIYAKU KK (JP) 1994-12-21 EP disclosed
EP-0596126-A1 NOVEL QUINOLONE DERIVATIVE OR SALT THEREOF AND ANTIBACTERIAL CONTAINING THE SAME WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1994-05-11 EP disclosed
US-5254685-A Tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1993-10-19 US disclosed
US-5245037-A Synthetic bactericides WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1993-09-14 US disclosed
EP-0470578-A1 Novel tricyclic compound or salts thereof, method for producing the same and antimicrobial agent containing the same WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1992-02-12 EP disclosed
EP-0393400-A1 Novel quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1990-10-24 EP disclosed