Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | PARG | Q86W56 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2838726 | 0.81 | BCAT1 (0.33) | PARG | |
| SCHEMBL2842351 | 0.80 | SMN1; SMN2 (0.33) | LRRK2 | |
| SCHEMBL2838234 | 0.80 | KDM4E (0.39) | GAA | |
| SCHEMBL10695874 | 0.80 | BCAT1 (0.34) | GAAATM | |
| SCHEMBL10695876 | 0.80 | BCAT1 (0.34) | GAAATM | |
| SCHEMBL9037404 | 0.80 | BCAT1 (0.48) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL38662770 | 0.79 | GAA (0.34) | GAAATM | |
| SCHEMBL10697818 | 0.79 | GAA (0.34) | GAAATM | |
| SCHEMBL2837079 | 0.78 | PDK2 (0.32) | LRRK2 | |
| SCHEMBL1573400 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0408382-B1 | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL IND LTD (JP) | 1996-09-18 | — | — | EP | disclosed |
| US-5127935-A | Halogen, phenyl and heterocycle substituents, agricultural use | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| US-5084084-A | Uracil and thiouracil derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0408382-A2 | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1991-01-16 | — | — | EP | disclosed |