Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7212354 | 0.99 | SETD7 (0.53) | SETD7KDM4EDRD2HTR2AHTR2C | |
| SCHEMBL9035520 | 0.87 | MEN1 (0.54) | SETD7KDM4ESIGMAR1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7213845 | 0.86 | MEN1 (0.53) | SETD7KDM4ESIGMAR1ALDH1A1LMNA | |
| SCHEMBL7300886 | 0.86 | SIGMAR1 (0.60) | SETD7DRD2HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL7212750 | 0.85 | SIGMAR1 (0.59) | SETD7DRD2HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL7217881 | 0.84 | SETD7 (0.57) | SETD7DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9035852 | 0.83 | SETD7 (0.68) | SETD7DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL9036519 | 0.82 | SETD7 (0.67) | SETD7KDM4EDRD2HTR2AHTR2C | |
| SCHEMBL9034769 | 0.82 | SETD7 (0.62) | SETD7KDM4EDRD2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL7213868 | 0.82 | SETD7 (0.66) | SETD7DRD2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371805-B1 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO KK (JP) | 1996-06-26 | — | — | EP | claimed |
| EP-0371805-A2 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1990-06-06 | — | — | EP | claimed |