Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6227535 | 0.81 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3TDP1HPGD | |
| SCHEMBL17842516 | 0.79 | CYP2C19 (0.47) | CYP2C19SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL29715183 | 0.79 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3TDP1HPGD | |
| SCHEMBL29715186 | 0.79 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3TDP1HPGD | |
| Hydrochloric Acid SCHEMBL27277418 | 0.78 | MAPT (0.39) | SLC6A2SLC6A4SLC6A3TDP1OPRK1 | |
| SCHEMBL11617245 | 0.76 | TSHR (0.50) | CYP2C19SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL5069784 | 0.75 | CYP2C19 (0.44) | CYP2C19SLC6A2SLC6A4SLC6A3TDP1 | |
| SCHEMBL11631926 | 0.75 | ALDH1A1 (0.60) | CYP2C19SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL14033619 | 0.74 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3OPRK1KCNA5 | |
| SCHEMBL14033203 | 0.73 | SLC6A2 (0.53) | CYP2C19SLC6A2SLC6A4SLC6A3OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695292-A1 | HERBICIDAL (4-SUBSTITUTED PYRIDYL)-3-CARBINOLS | ZENECA LIMITED (GB) | 1996-02-07 | — | — | EP | disclosed |