Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.59 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.59 |
| ▸ | PGR | P06401 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | SHBG | P04278 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tixocortol Pivalate SCHEMBL5484132 | 0.87 | NR3C1 (0.75) | HIF1ANR3C1NR3C2PGRCYP2C19 | |
| Tixocortol Pivalate SCHEMBL6828 | 0.87 | NR3C1 (0.75) | HIF1ANR3C1NR3C2PGRCYP2C19 | |
| Tixocortol Pivalate SCHEMBL6827 | 0.87 | NR3C1 (0.75) | HIF1ANR3C1NR3C2PGRCYP2C19 | |
| Tixocortol Pivalate SCHEMBL1792227 | 0.83 | HIF1A (0.69) | HIF1ANR3C1NR3C2PGRCYP2C19 | |
| Tixocortol Pivalate SCHEMBL16516121 | 0.78 | NR3C1 (0.72) | HIF1ANR3C1NR3C2PGRCYP2C19 | |
| Hydrocortisone SCHEMBL27426095 | 0.76 | HIF1A (0.89) | HIF1ANR3C1NR3C2PGRCYP2C19 | |
| SCHEMBL903430 | 0.76 | NR3C2 (0.80) | HIF1ANR3C1NR3C2PGRCYP2C19 | |
| SCHEMBL13332834 | 0.76 | NR3C2 (0.80) | HIF1ANR3C1NR3C2PGRCYP2C19 | |
| Hydrocortisone SCHEMBL24900238 | 0.75 | HIF1A (1.00) | HIF1ANR3C1NR3C2PGRCYP2C19 | |
| SCHEMBL12396665 | 0.75 | HIF1A (0.85) | HIF1ANR3C1NR3C2PGRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044832-A1 | METHODS OF TREATING A SUBJECT AND RELATED PARTICLES, POLYMERS AND COMPOSITIONS | FETZER OLIVER S (US) | 2012-04-05 | — | — | WO | disclosed |