Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034144 | 0.84 | NPC1 (0.42) | ALDH1A1LMNAL3MBTL1GAATHRB | |
| SCHEMBL8708193 | 0.76 | NPC1 (0.35) | ALDH1A1LMNAL3MBTL1GAATHRB | |
| SCHEMBL9033574 | 0.76 | NPC1 (0.42) | ALDH1A1LMNAL3MBTL1GAANPC1 | |
| SCHEMBL9040850 | 0.76 | NPC1 (0.42) | ALDH1A1LMNAL3MBTL1GAATHRB | |
| SCHEMBL8840520 | 0.74 | NPC1 (0.41) | ALDH1A1LMNAL3MBTL1GAATHRB | |
| SCHEMBL27451609 | 0.72 | KDM4E (0.35) | ALDH1A1L3MBTL1GAACYP1A2CYP2D6 | |
| SCHEMBL8416676 | 0.72 | JAK3 (0.35) | ALDH1A1LMNAL3MBTL1GAATHRB | |
| SCHEMBL8708679 | 0.70 | KCNA3 (0.38) | ALDH1A1LMNAL3MBTL1GAATHRB | |
| SCHEMBL8459743 | 0.67 | NQO1 (0.47) | ALDH1A1LMNAL3MBTL1GAANPC1 | |
| SCHEMBL8462620 | 0.66 | MAPT (0.45) | ALDH1A1LMNAL3MBTL1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719256-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007891-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |