Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034144 | 0.86 | NPC1 (0.42) | MEN1KMT2ACYP3A4NPC1SMN1; SMN2 | |
| SCHEMBL8708193 | 0.81 | NPC1 (0.35) | MEN1KMT2ACYP3A4NPC1SMN1; SMN2 | |
| SCHEMBL8708329 | 0.76 | KCNA3 (0.40) | KCNA3MEN1KMT2ACYP3A4KDM4E | |
| SCHEMBL8840512 | 0.75 | KCNA3 (0.38) | KCNA3MEN1KMT2ACYP3A4KDM4E | |
| SCHEMBL9034315 | 0.73 | JAK3 (0.33) | JAK3JAK2JAK1CHEK1NTRK1 | |
| SCHEMBL9040850 | 0.71 | NPC1 (0.42) | MEN1KMT2ACYP3A4NPC1ALDH1A1 | |
| SCHEMBL9033513 | 0.71 | KCNA3 (0.41) | KCNA3MEN1KMT2ACYP3A4KDM4E | |
| SCHEMBL8840445 | 0.70 | TRPM8 (0.35) | KCNA3MEN1KMT2ACYP3A4KDM4E | |
| Hydrochloric Acid SCHEMBL8704982 | 0.70 | KCNA3 (0.40) | KCNA3MEN1KMT2ACYP3A4KDM4E | |
| SCHEMBL9034701 | 0.70 | ALDH1A1 (0.41) | MEN1KMT2ACYP3A4NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723450-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1998-03-03 | — | — | US | disclosed |
| EP-0719256-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007891-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |