Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003879 | 0.81 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3PPARGPPARA | |
| SCHEMBL10051066 | 0.81 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3PPARGPPARA | |
| SCHEMBL10051069 | 0.81 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3PPARGPPARA | |
| SCHEMBL9864149 | 0.77 | SLC6A2 (0.52) | SLC6A4SLC6A2SLC6A3PPARGPPARA | |
| SCHEMBL6683952 | 0.74 | SLC6A3 (0.52) | SLC6A4SLC6A2SLC6A3PPARGPPARA | |
| SCHEMBL9481327 | 0.72 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3PPARGPPARA | |
| SCHEMBL27669076 | 0.72 | SLC6A4 (0.58) | SLC6A4SLC6A2SLC6A3PPARGPPARA | |
| SCHEMBL6465120 | 0.72 | MME (0.49) | SLC6A4PPARGPPARAHSD17B10MME | |
| SCHEMBL28615059 | 0.72 | MEN1 (0.44) | SLC6A4SLC6A2SLC6A3PPARGPPARA | |
| SCHEMBL25335313 | 0.70 | SLC6A2 (0.41) | SLC6A4SLC6A2SLC6A3PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719264-A1 | IMIDAZOLONE AND OXAZOLONE DERIVATIVES AS DOPAMINE ANTAGONISTS | MERCK SHARP & DOHME LTD. (GB) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007904-A1 | IMIDAZOLONE AND OXAZOLONE DERIVATIVES AS DOPAMINE ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1995-03-23 | — | — | WO | disclosed |