Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035893 | 0.88 | GSK3B (0.59) | POLBGSK3BSMN1; SMN2TP53THRB | |
| SCHEMBL9036405 | 0.86 | POLB (0.54) | POLBGSK3BSMN1; SMN2TP53THRB | |
| SCHEMBL9035177 | 0.86 | POLB (0.56) | POLBGSK3BSMN1; SMN2HDAC6 | |
| SCHEMBL9037918 | 0.85 | POLB (0.71) | POLBGSK3B | |
| SCHEMBL9035442 | 0.85 | POLB (0.53) | POLBGSK3BSMN1; SMN2TP53THRB | |
| SCHEMBL9034916 | 0.85 | POLB (0.60) | POLBGSK3BSMN1; SMN2TP53 | |
| SCHEMBL9037675 | 0.85 | POLB (0.60) | POLBGSK3BSMN1; SMN2 | |
| SCHEMBL9036646 | 0.84 | POLB (0.52) | POLBGSK3BTP53 | |
| SCHEMBL9035470 | 0.84 | POLB (0.52) | POLBGSK3BSMN1; SMN2 | |
| SCHEMBL9037232 | 0.84 | POLB (0.51) | POLBGSK3BSMN1; SMN2TP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492667-B1 | 1,4-Benzothiazine-2-acetic acid derivatives, processes for production thereof and their use | GREEN CROSS CORP (JP) | 1996-04-17 | — | — | EP | disclosed |
| US-5252571-A | 1,4-benzothiazine-2-acetic acid derivatives | SAPPORO BREWERIES LIMITED (JP) | 1993-10-12 | — | — | US | disclosed |
| EP-0492667-A1 | 1,4-Benzothiazine-2-acetic acid derivatives, processes for production thereof and their use | THE GREEN CROSS CORPORATION (JP) | 1992-07-01 | — | — | EP | disclosed |