Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493439 | 0.90 | GSK3B (0.55) | GSK3BTP53THRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9036405 | 0.89 | POLB (0.54) | GSK3BPOLBTP53THRBSMN1; SMN2 | |
| SCHEMBL9037176 | 0.89 | GSK3B (0.56) | GSK3BPOLBTP53THRBSMN1; SMN2 | |
| SCHEMBL9037918 | 0.88 | POLB (0.71) | GSK3BPOLB | |
| SCHEMBL9035003 | 0.88 | POLB (0.53) | GSK3BPOLBTP53THRBSMN1; SMN2 | |
| SCHEMBL9035442 | 0.88 | POLB (0.53) | GSK3BPOLBTP53THRBSMN1; SMN2 | |
| SCHEMBL9037675 | 0.87 | POLB (0.60) | GSK3BPOLBSMN1; SMN2MAPTTSHR | |
| SCHEMBL9034916 | 0.87 | POLB (0.60) | GSK3BPOLBTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9036646 | 0.87 | POLB (0.52) | GSK3BPOLBTP53MAPTLMNA | |
| SCHEMBL9035470 | 0.87 | POLB (0.52) | GSK3BPOLBSMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492667-B1 | 1,4-Benzothiazine-2-acetic acid derivatives, processes for production thereof and their use | GREEN CROSS CORP (JP) | 1996-04-17 | — | — | EP | disclosed |
| US-5252571-A | 1,4-benzothiazine-2-acetic acid derivatives | SAPPORO BREWERIES LIMITED (JP) | 1993-10-12 | — | — | US | disclosed |
| EP-0492667-A1 | 1,4-Benzothiazine-2-acetic acid derivatives, processes for production thereof and their use | THE GREEN CROSS CORPORATION (JP) | 1992-07-01 | — | — | EP | disclosed |