Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.30 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031813 | 0.99 | HRH3 (0.41) | HRH3KDM4ETDP1L3MBTL1ALDH1A1 | |
| SCHEMBL8703407 | 0.84 | HRH3 (0.39) | HRH3KDM4EALDH1A1NCF1 | |
| SCHEMBL8703126 | 0.84 | HRH3 (0.43) | HRH3KDM4ETDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9032919 | 0.80 | ALDH1A1 (0.40) | HRH3KDM4ETDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9035300 | 0.78 | CYP1A2 (0.33) | NCF1MAPK1 | |
| SCHEMBL8697899 | 0.78 | HRH3 (0.45) | HRH3KDM4ETDP1L3MBTL1ALDH1A1 | |
| SCHEMBL8699541 | 0.77 | HRH3 (0.43) | HRH3KDM4ETDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9034153 | 0.77 | CYP1A2 (0.33) | HRH3NCF1SMN1; SMN2GAAMAPK1 | |
| SCHEMBL8697765 | 0.75 | HRH3 (0.43) | HRH3KDM4ETDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9034048 | 0.75 | KDM4E (0.43) | HRH3KDM4ETDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |