Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.33 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033888 | 0.96 | ABCB1 (0.41) | ABCB1CA2KMT2AMEN1ATM | |
| SCHEMBL9035167 | 0.94 | CA2 (0.41) | ABCB1CA2CTSLCTSBKMT2A | |
| SCHEMBL9032745 | 0.93 | ABCB1 (0.39) | ABCB1CA2KMT2AMEN1ATM | |
| SCHEMBL9032739 | 0.90 | ABCB1 (0.40) | ABCB1KMT2AMEN1ATMPLA2G4A | |
| SCHEMBL9033882 | 0.90 | ABCB1 (0.42) | ABCB1CA2KMT2AMEN1ATM | |
| SCHEMBL9033588 | 0.89 | ABCB1 (0.40) | ABCB1CA2KMT2AMEN1ATM | |
| SCHEMBL9034612 | 0.87 | SMN1; SMN2 (0.39) | ABCB1KMT2AMEN1 | |
| SCHEMBL9034510 | 0.87 | ABCB1 (0.37) | ABCB1KMT2AMEN1ATMPLA2G4A | |
| SCHEMBL9035133 | 0.87 | ABCB1 (0.39) | ABCB1CA2KMT2AMEN1ATM | |
| SCHEMBL9034419 | 0.86 | ABCB1 (0.38) | ABCB1KMT2AMEN1ATMPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |