Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980927 | 0.89 | ITGB3 (0.54) | ITGB3ITGA2BKMT2AMEN1MAPT | |
| SCHEMBL7951737 | 0.85 | ITGB3 (0.72) | ITGB3ITGA2BKMT2AMEN1ALDH1A1 | |
| SCHEMBL7961103 | 0.85 | ITGB3 (0.72) | ITGB3ITGA2BKMT2AMEN1ALDH1A1 | |
| SCHEMBL7966945 | 0.85 | ITGB3 (0.72) | ITGB3ITGA2BKMT2AMEN1ALDH1A1 | |
| SCHEMBL7951602 | 0.85 | ITGB3 (0.72) | ITGB3ITGA2BKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7960021 | 0.85 | ITGB3 (0.71) | ITGB3ITGA2BKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7969571 | 0.85 | ITGB3 (0.71) | ITGB3ITGA2BKMT2AMEN1ALDH1A1 | |
| SCHEMBL7985151 | 0.84 | ITGB3 (0.62) | ITGB3ITGA2BKMT2AMEN1MAPT | |
| Acetic Acid SCHEMBL7963605 | 0.84 | ITGB3 (0.70) | ITGB3ITGA2BKMT2AMEN1ALDH1A1 | |
| SCHEMBL7981895 | 0.83 | ITGB3 (0.66) | ITGB3ITGA2BKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729460-A1 | SUBSTITUTED 5-RING HETEROCYCLES, THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-09-04 | — | — | EP | disclosed |