Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035774 | 0.87 | KDM4E (0.35) | KDM4EGRM2OPRM1TRPV6 | |
| SCHEMBL27449714 | 0.85 | MEN1 (0.32) | KDM4EGRM2MEN1KMT2A | |
| SCHEMBL9034971 | 0.83 | — | — | |
| SCHEMBL8840380 | 0.82 | KDM4E (0.34) | KDM4EOPRM1HCRTR2 | |
| SCHEMBL8840417 | 0.80 | GRM2 (0.34) | KDM4EGRM2OPRM1TRPV6 | |
| SCHEMBL8840484 | 0.80 | KDM4E (0.33) | KDM4EOPRM1TRPV6MGLL | |
| SCHEMBL9033878 | 0.78 | KDM4E (0.34) | KDM4ENR3C1GRM2OPRM1TRPV6 | |
| SCHEMBL8840416 | 0.77 | TP53 (0.35) | KDM4E | |
| SCHEMBL8840443 | 0.76 | L3MBTL1 (0.33) | GRM2 | |
| SCHEMBL8840454 | 0.75 | TP53 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719256-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995007891-A1 | SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-03-23 | — | — | WO | disclosed |