Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032268 | 0.90 | HRH3 (0.46) | HRH3ACACBL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8703126 | 0.84 | HRH3 (0.43) | HRH3L3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL9034551 | 0.82 | HRH3 (0.39) | HRH3ACACBL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL9034272 | 0.80 | ATM (0.45) | HRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL8697899 | 0.79 | HRH3 (0.45) | HRH3L3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL9034996 | 0.75 | HRH3 (0.43) | HRH3L3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL25156049 | 0.75 | HRH3 (0.48) | HRH3L3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL9035119 | 0.74 | HRH3 (0.39) | HRH3L3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL9032167 | 0.74 | HRH3 (0.44) | HRH3L3MBTL1ALDH1A1KDM4EMAPT | |
| SCHEMBL9031813 | 0.73 | HRH3 (0.41) | HRH3L3MBTL1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1121713-A | serine derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 1996-05-01 | — | — | CN | disclosed |
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |