Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.36 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.36 |
| ▸ | CACNA2D4 | Q7Z3S7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035580 | 1.00 | DRD1 (0.38) | DRD1HTR2ACACNB4CACNA1ACACNA1G | |
| SCHEMBL8601899 | 1.00 | DRD1 (0.38) | DRD1HTR2ACACNB4CACNA1ACACNA1G | |
| SCHEMBL8602566 | 1.00 | DRD1 (0.38) | DRD1HTR2ACACNB4CACNA1ACACNA1G | |
| SCHEMBL8601315 | 1.00 | DRD1 (0.38) | DRD1HTR2ACACNB4CACNA1ACACNA1G | |
| SCHEMBL8601902 | 1.00 | DRD1 (0.38) | DRD1HTR2ACACNB4CACNA1ACACNA1G | |
| SCHEMBL8602565 | 1.00 | DRD1 (0.38) | DRD1HTR2ACACNB4CACNA1ACACNA1G | |
| SCHEMBL8877685 | 0.93 | AKR1B1 (0.38) | DRD1HTTNPC1RAB9AMEN1 | |
| SCHEMBL9035761 | 0.89 | DRD1 (0.38) | DRD1HTR2ACACNB4CACNA1ACACNA1G | |
| SCHEMBL9035755 | 0.89 | DRD1 (0.38) | DRD1HTR2ACACNB4CACNA1ACACNA1G | |
| SCHEMBL9035768 | 0.89 | DRD1 (0.38) | DRD1HTR2ACACNB4CACNA1ACACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532178-B1 | Methanoanthracenes as dopamine antagonists | ZENECA LTD (GB) | 1996-10-16 | — | — | EP | disclosed |
| US-5455246-A | Treating neuropsychiatric disorders | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1995-10-03 | — | — | US | disclosed |
| US-5266570-A | Neuropsychiatric disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-11-30 | — | — | US | disclosed |
| EP-0532178-A1 | Methanoanthracenes as dopamine antagonists | ZENECA LIMITED (GB) | 1993-03-17 | — | — | EP | disclosed |