Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312855 | 0.88 | CA1 (0.42) | CA1CA12CA2CA9TDP1 | |
| SCHEMBL610682 | 0.85 | CA1 (0.50) | CA1CA12CA2CA9TDP1 | |
| SCHEMBL17075163 | 0.85 | CA1 (0.50) | CA1CA12CA2CA9TDP1 | |
| SCHEMBL2907470 | 0.84 | TSHR (0.44) | TDP1ALDH1A1KMT2ALMNATSHR | |
| SCHEMBL697643 | 0.83 | CA1 (0.42) | CA1CA12CA2CA9TDP1 | |
| SCHEMBL8694244 | 0.82 | ALDH1A1 (0.50) | CA1CA12CA2CA9TDP1 | |
| SCHEMBL9069149 | 0.81 | BLM (0.40) | CA1CA12CA2CA9TDP1 | |
| Bicarbonate SCHEMBL28723134 | 0.81 | CA1 (0.46) | CA1CA12CA2CA9TDP1 | |
| SCHEMBL7041198 | 0.80 | CA12 (0.39) | CA1CA12CA2CA9TDP1 | |
| SCHEMBL2347061 | 0.79 | RARB (0.42) | CA1CA12CA2CA9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |