Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 18/20 | 0.60 |
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | PTAFR | P25105 | 1/20 | 0.51 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309692 | 0.88 | SETD7 (0.51) | HRH1DRD2CHRM2HTR1ACHRM1 | |
| Azatadine SCHEMBL3721 | 0.76 | HRH1 (1.00) | HRH1DRD2CHRM2HTR1ACHRM1 | |
| Azatadine SCHEMBL29746602 | 0.76 | HRH1 (1.00) | HRH1DRD2CHRM2HTR1ACHRM1 | |
| Azatadine SCHEMBL29363595 | 0.76 | HRH1 (1.00) | HRH1DRD2CHRM2HTR1ACHRM1 | |
| SCHEMBL7300338 | 0.76 | SETD7 (0.64) | HRH1DRD2CHRM2HTR1ACHRM1 | |
| SCHEMBL7306822 | 0.76 | SETD7 (0.45) | HRH1 | |
| SCHEMBL7300258 | 0.75 | SETD7 (0.52) | HRH1DRD2CHRM2HTR1ACHRM1 | |
| SCHEMBL7309778 | 0.75 | SETD7 (0.66) | HRH1DRD2CHRM2HTR1ACHRM1 | |
| SCHEMBL9034738 | 0.75 | SETD7 (0.66) | HRH1DRD2CHRM2HTR1ACHRM1 | |
| SCHEMBL9034364 | 0.75 | SETD7 (0.66) | HRH1DRD2CHRM2HTR1ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371805-B1 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO KK (JP) | 1996-06-26 | — | — | EP | claimed |
| EP-0371805-A2 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1990-06-06 | — | — | EP | claimed |
| US-5250681-A | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1993-10-05 | — | — | US | disclosed |