Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.80 |
| ▸ | DRD2 | P14416 | 1/20 | 0.80 |
| ▸ | HTR2A | P28223 | 1/20 | 0.80 |
| ▸ | HTR7 | P34969 | 1/20 | 0.80 |
| ▸ | HTR6 | P50406 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9694494 | 0.99 | HTR1A (0.78) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9036224 | 0.97 | HTR1A (0.74) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9383206 | 0.90 | HTR1A (0.98) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9382217 | 0.89 | HTR1A (0.96) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9596437 | 0.88 | HTR1A (0.98) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9207622 | 0.87 | HTR1A (0.85) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9202027 | 0.87 | HTR1A (0.75) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9209048 | 0.87 | HTR1A (0.69) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9380668 | 0.87 | HTR1A (0.72) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9390800 | 0.86 | HTR1A (0.84) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225412-A | Antipsychotic | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-07-06 | — | — | US | claimed |
| EP-0511610-B1 | Benzisothiazole- and benzisoxazole-3-carboxamides, a process for their preparation and their use as antipsychotic medicaments | HOECHST ROUSSEL PHARMA (US) | 1996-09-11 | — | — | EP | disclosed |
| EP-0511610-A1 | Benzisothiazole- and benzisoxazole-3-carboxamides, a process for their preparation and their use as antipsychotic medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-11-04 | — | — | EP | disclosed |