Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 10/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 10/20 | 0.51 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PTAFR | P25105 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PDE1A | P54750 | 1/20 | 0.51 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.51 |
| ▸ | PDE2A | O00408 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035282 | 0.90 | PDE3B (0.55) | ALDH1A1PDE3BPDE3AHPGDHSD17B10 | |
| SCHEMBL9036125 | 0.84 | PDE3B (0.61) | ALDH1A1PDE3BPDE3AHPGDHSD17B10 | |
| SCHEMBL11066631 | 0.81 | PDE3B (0.63) | ALDH1A1PDE3BPDE3AHPGDHSD17B10 | |
| SCHEMBL11062114 | 0.81 | PDE3B (0.60) | ALDH1A1PDE3BPDE3AHPGDHSD17B10 | |
| SCHEMBL11071229 | 0.80 | PDE3B (0.67) | ALDH1A1PDE3BPDE3AHPGDHSD17B10 | |
| SCHEMBL11065347 | 0.78 | PDE3B (0.65) | ALDH1A1PDE3BPDE3AHPGDHSD17B10 | |
| SCHEMBL9036841 | 0.76 | PDE3B (0.62) | ALDH1A1PDE3BPDE3AHPGDHSD17B10 | |
| SCHEMBL9035303 | 0.76 | PDE3B (0.59) | ALDH1A1PDE3BPDE3AHPGDHSD17B10 | |
| SCHEMBL9036168 | 0.74 | PDE3B (0.64) | ALDH1A1PDE3BPDE3AHPGDHSD17B10 | |
| SCHEMBL9037169 | 0.74 | PDE3B (0.53) | ALDH1A1PDE3BPDE3AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |