Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 10/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 10/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.65 |
| ▸ | HPGD | P15428 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | PDE5A | O76074 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | PTAFR | P25105 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | PDE1A | P54750 | 1/20 | 0.65 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071229 | 0.97 | PDE3B (0.67) | PDE3BPDE3AALDH1A1HPGDKDM4E | |
| SCHEMBL11066631 | 0.95 | PDE3B (0.63) | PDE3BPDE3AALDH1A1HPGDKDM4E | |
| SCHEMBL11062114 | 0.85 | PDE3B (0.60) | PDE3BPDE3AALDH1A1HPGDKDM4E | |
| SCHEMBL11319201 | 0.80 | PDE3B (0.73) | PDE3BPDE3AALDH1A1HPGDKDM4E | |
| Cilostamide SCHEMBL29491047 | 0.79 | PDE3B (1.00) | PDE3BPDE3AALDH1A1HPGDKDM4E | |
| Cilostamide SCHEMBL49742 | 0.79 | PDE3B (1.00) | PDE3BPDE3AALDH1A1HPGDKDM4E | |
| SCHEMBL11317158 | 0.79 | PDE3B (1.00) | PDE3BPDE3AALDH1A1HPGDKDM4E | |
| SCHEMBL11342927 | 0.78 | PDE3B (0.83) | PDE3BPDE3AALDH1A1HPGDKDM4E | |
| SCHEMBL9036675 | 0.78 | ALDH1A1 (0.51) | PDE3BPDE3AALDH1A1HPGDKDM4E | |
| SCHEMBL11058784 | 0.78 | PDE3B (0.66) | PDE3BPDE3AALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |