Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | APP | P05067 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | WNT3A | P56704 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14554383 | 0.85 | CYP1A2 (0.55) | LMNACYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL11011214 | 0.81 | CYP1A2 (0.48) | LMNACYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL11152793 | 0.78 | NPC1 (0.54) | LMNACYP1A2CYP2C19CYP3A4RAB9A | |
| SCHEMBL4512266 | 0.77 | NPC1 (0.45) | LMNACYP1A2CYP3A4CYP2D6RAB9A | |
| SCHEMBL24086123 | 0.76 | CYP1A2 (0.51) | LMNACYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL5351987 | 0.75 | CYP1A2 (0.61) | CYP1A2CYP2C19CYP3A4PDK1RAB9A | |
| SCHEMBL14484796 | 0.75 | CYP1A2 (0.60) | LMNACYP1A2CYP2C19RAB9AGAA | |
| SCHEMBL2055225 | 0.75 | APP (0.79) | APPGLAGAA | |
| SCHEMBL9037879 | 0.74 | NPC1 (0.53) | LMNACYP1A2CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL21566144 | 0.73 | APP (0.72) | APPGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690857-A1 | CYCLIC AMIDE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDAL COMPOSITIONS CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994013665-A1 | CYCLIC AMIDE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND HERBICIDAL COMPOSITIONS CONTAINING THEM | ISHIHARA SANGYO KAISHA LTD. (JP) | 1994-06-23 | — | — | WO | disclosed |