Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9036775 | 0.85 | LMNA (0.55) | CYP1A2CYP2C19CYP3A4PDK1APP | |
| SCHEMBL11011214 | 0.81 | CYP1A2 (0.48) | CYP1A2CYP2C19CYP3A4PDK1APP | |
| SCHEMBL14554495 | 0.77 | NPC1 (0.49) | CYP1A2CYP2C19CYP3A4APPRAB9A | |
| SCHEMBL14484796 | 0.77 | CYP1A2 (0.60) | CYP1A2CYP2C19RAB9ALMNAGAA | |
| SCHEMBL24086123 | 0.75 | CYP1A2 (0.51) | CYP1A2CYP2C19CYP3A4PDK1APP | |
| SCHEMBL3242801 | 0.74 | CYP1A2 (0.64) | CYP1A2CYP2C19CYP3A4PDK1APP | |
| SCHEMBL23965817 | 0.73 | SMN1; SMN2 (0.48) | CYP1A2RAB9ALMNAGLAGAA | |
| SCHEMBL29683488 | 0.71 | CYP3A4 (1.00) | CYP1A2CYP2C19CYP3A4PDK1APP | |
| SCHEMBL22358 | 0.71 | CYP3A4 (1.00) | CYP1A2CYP2C19CYP3A4PDK1APP | |
| SCHEMBL3752321 | 0.70 | SMN1; SMN2 (0.51) | APPRAB9ALMNAGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013006408-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-01-10 | — | — | WO | disclosed |