Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | THRB | P10828 | 1/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17313683 | 0.77 | MAPT (0.73) | KMT2ALMNAALDH1A1HTTUSP2 | |
| SCHEMBL9037392 | 0.76 | ALDH1A1 (0.58) | KMT2ALMNAALDH1A1HTTUSP2 | |
| SCHEMBL8122651 | 0.75 | KCNH2 (1.00) | KMT2ALMNAALDH1A1HTTUSP2 | |
| SCHEMBL16727520 | 0.74 | TSHR (0.73) | KMT2ALMNAALDH1A1HTTUSP2 | |
| SCHEMBL15539933 | 0.74 | TSHR (0.73) | KMT2ALMNAALDH1A1HTTUSP2 | |
| SCHEMBL15275436 | 0.74 | KMT2A (0.83) | KMT2ALMNAALDH1A1HTTUSP2 | |
| SCHEMBL9186776 | 0.73 | KMT2A (0.62) | KMT2ALMNAALDH1A1HTTUSP2 | |
| SCHEMBL9183149 | 0.73 | KMT2A (0.62) | KMT2ALMNAALDH1A1HTTUSP2 | |
| SCHEMBL9185511 | 0.73 | KMT2A (0.60) | KMT2ALMNAALDH1A1HTTUSP2 | |
| SCHEMBL9188119 | 0.73 | KMT2A (0.57) | KMT2ALMNAALDH1A1HTTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691962-A1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-17 | — | — | EP | disclosed |