Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GLS | O94925 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42224 | 0.78 | GLS (0.51) | TP53GAAHTTRAB9AALDH1A1 | |
| SCHEMBL1285658 | 0.78 | GLS (0.51) | TP53GAAHTTRAB9AALDH1A1 | |
| SCHEMBL43071 | 0.78 | GLS (0.51) | TP53GAAHTTRAB9AALDH1A1 | |
| SCHEMBL9034901 | 0.73 | GLS (0.41) | POLBHTTGLSMAPT | |
| SCHEMBL9035836 | 0.71 | HTT (0.43) | POLBKDM4EHTTL3MBTL1ALDH1A1 | |
| SCHEMBL9036013 | 0.71 | TSHR (0.43) | TP53RAB9ASMN1; SMN2GLSLMNA | |
| SCHEMBL9035188 | 0.70 | CYP19A1 (0.46) | POLBKDM4EALOX15HTTRAB9A | |
| SCHEMBL11631164 | 0.69 | CA12 (0.42) | POLBKDM4ETP53GAAALOX15 | |
| SCHEMBL42111 | 0.67 | GLS (0.49) | TP53GAAHTTRAB9AALDH1A1 | |
| SCHEMBL9036084 | 0.67 | GLS (0.49) | TP53GAAHTTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0362902-B1 | Process and intermediates for beta-lactam antibiotics | HARVARD COLLEGE (US) | 1996-01-17 | — | — | EP | disclosed |
| EP-0209352-B1 | PROCESS AND INTERMEDIATES FOR BETA-LACTAM ANTIBIOTICS | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1991-05-02 | — | — | EP | disclosed |
| EP-0362902-A2 | Process and intermediates for beta-lactam antibiotics | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1990-04-11 | — | — | EP | disclosed |
| US-4870169-A | Intermediates for beta-lactam antibiotics | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1989-09-26 | — | — | US | disclosed |
| US-4775752-A | Process and intermediates for beta-lactam antibiotics | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1988-10-04 | — | — | US | disclosed |
| US-4734495-A | Process and intermediates for beta-lactam antibiotics | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1988-03-29 | — | — | US | disclosed |
| US-4665171-A | CARBACEPHALOSPORINS | HARVARD UNIVERSITY (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0209352-A2 | Process and intermediates for beta-lactam antibiotics | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1987-01-21 | — | — | EP | disclosed |