Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20873451 | 0.78 | CCNB2 (0.39) | — | |
| SCHEMBL674404 | 0.76 | CYP2D6 (0.38) | CHRM1 | |
| SCHEMBL27818098 | 0.75 | TDP1 (0.45) | CHRM1CHRM2LMNASMN1; SMN2 | |
| SCHEMBL1074604 | 0.73 | TDP1 (0.47) | CHRM1CHRM2LMNA | |
| SCHEMBL997911 | 0.71 | CYP2D6 (0.39) | CHRM1NPC1LMNA | |
| SCHEMBL28521019 | 0.70 | TLR8 (0.41) | NFKB1NFKB2RELANPC1LMNA | |
| SCHEMBL9042054 | 0.69 | CHRM1 (0.47) | CHRM1CHRM2 | |
| SCHEMBL10496018 | 0.69 | TDP1 (0.40) | CHRM1CHRM2LMNA | |
| SCHEMBL293478 | 0.69 | TDP1 (0.40) | CHRM1CHRM2LMNA | |
| SCHEMBL7324144 | 0.69 | NR5A1 (0.66) | NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |