SCHEMBL9037270

SCHEMBL9037270

Cc1ccc(CCNc2ncnc(C(C)F)c2Cl)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GALR3 O60755 1/20 0.59
LMNA P02545 5/20 0.49
TP53 P04637 3/20 0.49
HTT P42858 6/20 0.43
RAB9A P51151 1/20 0.43
AURKA O14965 1/20 0.42
AURKB Q96GD4 1/20 0.42
TTBK1 Q5TCY1 2/20 0.42
TTBK2 Q6IQ55 2/20 0.42
MEN1 O00255 1/20 0.41
TSHR P16473 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPT P10636 3/20 0.41
NR2F2 P24468 1/20 0.40
EGFR P00533 1/20 0.38
APP P05067 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9036534 0.91 GALR3 (0.50) GALR3LMNATP53HTTRAB9A
SCHEMBL9037262 0.90 GALR3 (0.59) GALR3LMNATP53HTTRAB9A
SCHEMBL8401676 0.88 RAB9A (0.57) GALR3LMNATP53HTTRAB9A
SCHEMBL9038336 0.88 GALR3 (0.57) GALR3LMNATP53HTTRAB9A
SCHEMBL8485751 0.88 HTT (0.51) GALR3LMNATP53HTTRAB9A
SCHEMBL8025185 0.86 PRMT1 (0.48) GALR3LMNATP53HTTMEN1
SCHEMBL9039150 0.86 PDE2A (0.46) GALR3LMNAHTTRAB9AAURKA
SCHEMBL9037695 0.86 TP53 (0.51) GALR3LMNATP53HTTRAB9A
Flufenerim SCHEMBL29429245 0.83 CYP3A4 (0.42) GALR3LMNATP53HTTRAB9A
Flufenerim SCHEMBL26581 0.83 CYP3A4 (0.42) GALR3LMNATP53HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665225-B1 4-Phenethylamino pyrimidine derivative, process for preparing the same and agricultural and horticultural chemical for controlling noxious organisms containing the same UBE INDUSTRIES (JP) 1996-11-27 EP disclosed
US-5498612-A INSECTICIDE, ACARICIDE, FUNGICIDE, NEMATOCIDE UBE INDUSTRIES, LTD. (JP) 1996-03-12 US disclosed
EP-0665225-A1 4-Phenethylamino pyrimidine derivative, process for preparing the same and agricultural and horticultural chemical for controlling noxious organisms containing the same UBE INDUSTRIES, LTD. (JP) 1995-08-02 EP disclosed