Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 6/20 | 0.80 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.80 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL6956900 | 0.97 | KCNK3 (0.76) | KCNK3KCNK9MEN1KMT2AMAPT | |
| SCHEMBL8572023 | 0.90 | MEN1 (0.78) | KCNK3KCNK9MEN1KMT2AMAPT | |
| Iodide SCHEMBL6957570 | 0.89 | MEN1 (0.76) | KCNK3KCNK9MEN1KMT2AMAPT | |
| SCHEMBL6958482 | 0.89 | MEN1 (0.71) | KCNK3KCNK9MEN1KMT2AMAPT | |
| SCHEMBL7084928 | 0.86 | KCNK3 (0.58) | KCNK3KCNK9MEN1KMT2AMAPT | |
| SCHEMBL6962792 | 0.85 | KCNK3 (0.54) | KCNK3KCNK9MEN1KMT2AMAPT | |
| Oxalic Acid SCHEMBL27363239 | 0.85 | KCNK3 (0.58) | KCNK3KCNK9MEN1KMT2AMAPT | |
| Oxalic Acid SCHEMBL6956873 | 0.84 | KCNK3 (0.56) | KCNK3KCNK9MEN1KMT2AMAPT | |
| SCHEMBL12259170 | 0.81 | KCNK3 (0.84) | KCNK3KCNK9MEN1KMT2AMAPT | |
| SCHEMBL6280367 | 0.81 | RAB9A (0.53) | KCNK3KCNK9MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071746-C | Amidine derivatives with nitric oxide synthetase activities | ASTERA CO (SE) | 2001-09-26 | — | — | CN | claimed |
| CN-1132505-A | Amidine derivatives with nitric oxide synthetase activities | ASTERA CO (SE) | 1996-10-02 | — | — | CN | claimed |
| EP-0713483-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | Astra Aktiebolag (SE) | 1996-05-29 | — | — | EP | claimed |
| WO-1995005363-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | ASTRA AKTIEBOLAG (SE) | 1995-02-23 | — | — | WO | claimed |