Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 10/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8792057 | 0.95 | ADRB2 (0.47) | ADRB2SERPINE1ADRB3ADRB1CCR2 | |
| SCHEMBL8792055 | 0.95 | ADRB2 (0.47) | ADRB2SERPINE1ADRB3ADRB1CCR2 | |
| SCHEMBL8791348 | 0.92 | ADRB2 (0.49) | ADRB2SERPINE1ADRB3ADRB1CCR2 | |
| SCHEMBL8697353 | 0.92 | ADRB3 (0.54) | ADRB2ADRB3ADRB1ADRA1DADRA1A | |
| SCHEMBL8697346 | 0.92 | ADRB3 (0.54) | ADRB2ADRB3ADRB1ADRA1DADRA1A | |
| SCHEMBL8697349 | 0.92 | ADRB3 (0.54) | ADRB2ADRB3ADRB1ADRA1DADRA1A | |
| SCHEMBL8791657 | 0.91 | ADRB2 (0.46) | ADRB2SERPINE1ADRB3ADRB1ADRA1D | |
| SCHEMBL8792124 | 0.91 | ADRB2 (0.47) | ADRB2SERPINE1ADRB3ADRB1ADRA1D | |
| SCHEMBL8793420 | 0.89 | ADRB2 (0.46) | ADRB2SERPINE1ADRB3ADRB1ADRA1D | |
| SCHEMBL8792361 | 0.88 | ADRB2 (0.50) | ADRB2SERPINE1ADRB3ADRB1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703911-A1 | SECONDARY AMINES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | PFIZER (US) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029290-A1 | SECONDARY AMINES AS ANTIDIABETIC AND ANTIOBESITY AGENTS | PFIZER INC. (US) | 1994-12-22 | — | — | WO | disclosed |