Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29362376 | 0.89 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL10093017 | 0.89 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL9036015 | 0.85 | CNR1 (0.74) | CNR1CNR2 | |
| SCHEMBL6860387 | 0.81 | CNR1 (0.84) | CNR1CNR2 | |
| SCHEMBL15112472 | 0.81 | CNR2 (0.79) | CNR1CNR2 | |
| SCHEMBL9640540 | 0.81 | CNR1 (0.83) | CNR1CNR2 | |
| SCHEMBL11903692 | 0.80 | CNR2 (0.79) | CNR1CNR2 | |
| SCHEMBL17025802 | 0.80 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL2075393 | 0.78 | CNR2 (1.00) | CNR1CNR2 | |
| SCHEMBL15112248 | 0.77 | CNR2 (0.70) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445781-B1 | 3-Arylcarbonyl-1-aminoalkyl-1H-indole containing antiglaucoma compositions | STERLING WINTHROP INC (US) | 1996-01-31 | — | — | EP | disclosed |
| EP-0445781-A1 | 3-Arylcarbonyl-1-aminoalkyl-1H-indole containing antiglaucoma compositions | STERLING WINTHROP INC. (US) | 1991-09-11 | — | — | EP | disclosed |
| US-5013837-A | Treatment of glaucoma | STERLING DRUG INC. (US) | 1991-05-07 | — | — | US | disclosed |
| US-4973587-A | 3-arylcarbonyl-1-aminoalkyl-1H-indole-containing antiglaucoma method | STERLING DRUG INC. (US) | 1990-11-27 | — | — | US | disclosed |