SCHEMBL9640540

SCHEMBL9640540

O=C(c1cccc2ccccc12)c1cccc2c1ccn2CCN1CCOCC1

nearest known ligand 0.83

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 6/20 0.83
CNR2 P34972 3/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10093017 0.91 CNR1 (1.00) CNR1CNR2
SCHEMBL29362376 0.91 CNR1 (1.00) CNR1CNR2
Water SCHEMBL9640478 0.88 CNR1 (0.65) CNR1CNR2
SCHEMBL9641362 0.86 CNR1 (0.62) CNR1CNR2
Hydrochloric Acid SCHEMBL9640773 0.85 CNR1 (0.61) CNR1CNR2
SCHEMBL15999004 0.84 CNR1 (0.59) CNR1CNR2
SCHEMBL6860387 0.81 CNR1 (0.84) CNR1CNR2
SCHEMBL17025802 0.81 CNR1 (1.00) CNR1CNR2
SCHEMBL9037660 0.81 CNR1 (1.00) CNR1CNR2
SCHEMBL15997747 0.80 CNR1 (0.68) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0278265-B1 1- [(4-Morpholinyl) alkyl] -1H-indoles useful as analgesics and preparation thereof STERLING WINTHROP INC. (US) 1992-09-09 EP claimed
US-5081122-A Antiglaucoma compositions containing 4-arylcarbonyl-1-(4-morpholinyl)-lower-alkyl)-1H-indoles and method of use thereof STERLING DRUG INC. (US) 1992-01-14 US claimed
US-4840950-A ANALGESICS STERLING DRUG INC. (US) 1989-06-20 US claimed
EP-0278265-A1 1- [(4-Morpholinyl) alkyl] -1H-indoles useful as analgesics and preparation thereof STERLING WINTHROP INC. (US) 1988-08-17 EP claimed