Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120232 | 0.82 | CYP1A2 (0.58) | CYP1A2KDM4EALOX15KMT2ACYP3A4 | |
| SCHEMBL516178 | 0.82 | CYP1A2 (0.49) | CYP1A2KDM4EALOX15KMT2ACYP3A4 | |
| SCHEMBL10359832 | 0.81 | CYP1A2 (0.47) | CYP1A2KDM4EALOX15KMT2ACYP3A4 | |
| SCHEMBL515976 | 0.75 | CYP1A2 (0.48) | CYP1A2KDM4EALOX15KMT2ACYP3A4 | |
| SCHEMBL7774964 | 0.75 | CYP1A2 (0.44) | CYP1A2KDM4EALOX15KMT2ACYP3A4 | |
| SCHEMBL4527245 | 0.74 | CYP1A2 (0.54) | CYP1A2KDM4EKMT2ACYP2D6SLC6A2 | |
| SCHEMBL4248685 | 0.72 | CYP1A2 (0.46) | CYP1A2KDM4EALOX15KMT2ACYP3A4 | |
| SCHEMBL6693445 | 0.72 | ALOX15 (0.46) | CYP1A2KDM4EALOX15KMT2ACYP3A4 | |
| SCHEMBL31390272 | 0.72 | CYP1A2 (0.46) | CYP1A2KDM4EALOX15KMT2ACYP3A4 | |
| SCHEMBL16991809 | 0.72 | CYP1A2 (0.46) | CYP1A2KDM4EALOX15KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039682-A | Sulfoalkyl ether-alkyl ether cyclodextrin derivatives | UNIV KANSAS (US) | 2007-09-19 | — | — | CN | disclosed |
| EP-0741705-A1 | 4-(2-(3-ARYLOXY-2-HYDROXYPROPYLAMINO ALKYLOXY)-5-NITROPHENYL)-1,4-DIHYDROPYRIDINES AS ANTIHYPERTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |