Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 14/20 | 0.61 |
| ▸ | DRD2 | P14416 | 13/20 | 0.61 |
| ▸ | DRD4 | P21917 | 9/20 | 0.61 |
| ▸ | DRD1 | P21728 | 3/20 | 0.60 |
| ▸ | HTR7 | P34969 | 2/20 | 0.60 |
| ▸ | DRD5 | P21918 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9042871 | 0.95 | DRD3 (0.59) | DRD3DRD2DRD4DRD1HTR7 | |
| SCHEMBL9038875 | 0.83 | DRD3 (0.70) | DRD3DRD2DRD4DRD1HTR7 | |
| Hydrochloric Acid SCHEMBL9041792 | 0.82 | DRD3 (0.68) | DRD3DRD2DRD4DRD1HTR7 | |
| SCHEMBL9039623 | 0.80 | DRD3 (0.54) | DRD3DRD2DRD4DRD1HTR7 | |
| SCHEMBL9043055 | 0.77 | MAOB (0.45) | DRD3HTR7CYP3A4HTR1ACYP2D6 | |
| Water SCHEMBL9040179 | 0.76 | MAOB (0.44) | DRD3HTR7CYP3A4HTR1ACYP2D6 | |
| SCHEMBL13448967 | 0.75 | DRD3 (0.80) | DRD3DRD2DRD4DRD1HTR7 | |
| SCHEMBL13448975 | 0.75 | DRD3 (0.79) | DRD3DRD2DRD4DRD1HTR7 | |
| Oxalic Acid SCHEMBL9038590 | 0.75 | DRD3 (0.48) | DRD3DRD2DRD4DRD1HTR7 | |
| SCHEMBL9039373 | 0.74 | HTT (0.40) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465254-B1 | Fused thiophene compounds and uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-11-13 | — | — | EP | claimed |
| EP-0465254-A1 | Fused thiophene compounds and uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-01-08 | — | — | EP | claimed |
| US-5141930-A | Antianxietic drug, antipsychotics and cardiotonic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-08-25 | — | — | US | disclosed |