Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.54 |
| ▸ | DRD2 | P14416 | 8/20 | 0.53 |
| ▸ | DRD1 | P21728 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 7/20 | 0.49 |
| ▸ | HTR2A | P28223 | 4/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9038590 | 0.94 | DRD3 (0.48) | DRD3DRD2DRD1HTR1AHTR2A | |
| Fumaric Acid SCHEMBL9038033 | 0.93 | DRD3 (0.48) | DRD3DRD2DRD1HTR1AHTR2A | |
| Fumaric Acid SCHEMBL9038032 | 0.93 | DRD3 (0.48) | DRD3DRD2DRD1HTR1AHTR2A | |
| SCHEMBL9038296 | 0.89 | DRD3 (0.55) | DRD3DRD2DRD1HTR1AHTR2A | |
| SCHEMBL9038835 | 0.88 | DRD3 (0.53) | DRD3DRD2DRD1HTR1AHTR2A | |
| SCHEMBL9039129 | 0.86 | DRD3 (0.51) | DRD3DRD2DRD1HTR1AHTR2A | |
| SCHEMBL9039322 | 0.83 | HTR1A (0.56) | DRD3DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL9038573 | 0.82 | DRD3 (0.63) | DRD3DRD2DRD1HTR1AHTR2A | |
| SCHEMBL9038713 | 0.81 | DRD3 (0.59) | DRD3DRD2DRD1HTR1AHTR2A | |
| SCHEMBL9668307 | 0.81 | HTR1A (0.42) | DRD3DRD2HTR1AHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465254-B1 | Fused thiophene compounds and uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-11-13 | — | — | EP | disclosed |
| US-5141930-A | Antianxietic drug, antipsychotics and cardiotonic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| EP-0465254-A1 | Fused thiophene compounds and uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |