Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9041559 | 1.00 | LMNA (0.59) | LMNANR1I2MAPTHSD17B10TLR8 | |
| SCHEMBL9853306 | 1.00 | LMNA (0.59) | LMNANR1I2MAPTHSD17B10TLR8 | |
| SCHEMBL18250739 | 1.00 | LMNA (0.59) | LMNANR1I2MAPTHSD17B10TLR8 | |
| SCHEMBL9853312 | 1.00 | LMNA (0.59) | LMNANR1I2MAPTHSD17B10TLR8 | |
| SCHEMBL19911314 | 0.94 | LMNA (0.67) | LMNANR1I2MAPTHSD17B10TLR8 | |
| SCHEMBL21378150 | 0.94 | MAPT (0.58) | LMNANR1I2MAPTHSD17B10SMN1; SMN2 | |
| SCHEMBL18250720 | 0.88 | LMNA (0.59) | LMNANR1I2MAPTHSD17B10TLR8 | |
| SCHEMBL31066861 | 0.88 | LMNA (0.59) | LMNANR1I2MAPTHSD17B10TLR8 | |
| SCHEMBL19296053 | 0.87 | LMNA (0.53) | LMNAMAPTHSD17B10SMN1; SMN2HPGD | |
| SCHEMBL19911329 | 0.86 | LMNA (0.48) | LMNANR1I2MAPTHSD17B10TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262343-B1 | N-alkylated quaternary nitrogen-containing heterocycles, process for their preparation and their use in pharmaceutical compositions | PUETTER MEDICE CHEM PHARM (DE) | 1996-01-03 | — | — | EP | disclosed |