Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 13/20 | 0.63 |
| ▸ | DRD2 | P14416 | 8/20 | 0.63 |
| ▸ | DRD1 | P21728 | 4/20 | 0.63 |
| ▸ | HTR1A | P08908 | 5/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9039040 | 0.97 | DRD3 (0.62) | DRD3DRD2DRD1HTR1ADRD4 | |
| SCHEMBL9038363 | 0.94 | DRD2 (0.54) | DRD3DRD2DRD1HTR1ADRD4 | |
| SCHEMBL9037898 | 0.89 | DRD3 (0.64) | DRD3DRD2DRD1HTR1ADRD4 | |
| SCHEMBL9037766 | 0.88 | DRD3 (0.61) | DRD3DRD2DRD1HTR1ADRD4 | |
| SCHEMBL9038557 | 0.86 | DRD3 (0.59) | DRD3DRD2DRD1HTR1ADRD4 | |
| SCHEMBL9038290 | 0.85 | DRD3 (0.58) | DRD3DRD2DRD1HTR1ADRD4 | |
| SCHEMBL9039637 | 0.85 | DRD3 (0.57) | DRD3DRD2DRD1HTR1ADRD4 | |
| SCHEMBL9039179 | 0.85 | DRD3 (0.57) | DRD3DRD2DRD1HTR1ADRD4 | |
| SCHEMBL9039114 | 0.85 | DRD3 (0.57) | DRD3DRD2DRD1HTR1ADRD4 | |
| SCHEMBL9039670 | 0.85 | DRD3 (0.57) | DRD3DRD2DRD1HTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0465254-B1 | Fused thiophene compounds and uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-11-13 | — | — | EP | claimed |
| US-5141930-A | Antianxietic drug, antipsychotics and cardiotonic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-08-25 | — | — | US | claimed |
| EP-0465254-A1 | Fused thiophene compounds and uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-01-08 | — | — | EP | claimed |
| EP-0465254-B1 | Fused thiophene compounds and uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-11-13 | — | — | EP | disclosed |
| US-5141930-A | Antianxietic drug, antipsychotics and cardiotonic agents | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| EP-0465254-A1 | Fused thiophene compounds and uses thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |