Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 7/20 | 0.46 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040808 | 0.82 | SCN9A (0.39) | CCKBRCCKARSMN1; SMN2MEN1KMT2A | |
| SCHEMBL9040545 | 0.80 | CCKBR (0.45) | CCKBRSMN1; SMN2 | |
| SCHEMBL7565985 | 0.78 | CCKBR (0.50) | CCKBR | |
| SCHEMBL7599335 | 0.78 | CCKBR (0.50) | CCKBR | |
| SCHEMBL10498966 | 0.75 | CCKBR (0.49) | CCKBR | |
| SCHEMBL11133819 | 0.75 | CCKBR (0.49) | CCKBR | |
| SCHEMBL7598579 | 0.75 | CCKBR (0.47) | CCKBR | |
| SCHEMBL7598575 | 0.75 | CCKBR (0.47) | CCKBR | |
| SCHEMBL7568437 | 0.74 | CCKBR (0.46) | CCKBRCCKAR | |
| SCHEMBL10499355 | 0.74 | CCKBR (0.46) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703222-A1 | 3-AMINOAZEPINE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-03-27 | — | — | EP | disclosed |