Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14842450 | 0.83 | HDAC6 (0.34) | CA1CA2CA7HDAC6HDAC1 | |
| SCHEMBL28012697 | 0.81 | HDAC6 (0.33) | AAK1CA1CA2CA7HDAC6 | |
| SCHEMBL17079771 | 0.80 | NOS1 (0.33) | CA1CA2CA7HDAC6HDAC1 | |
| SCHEMBL14842276 | 0.80 | HDAC6 (0.33) | CA1CA2CA7HDAC6HDAC1 | |
| SCHEMBL2713474 | 0.80 | HDAC6 (0.33) | CA1CA2CA7HDAC6HDAC1 | |
| SCHEMBL2713471 | 0.80 | HDAC6 (0.33) | CA1CA2CA7HDAC6HDAC1 | |
| SCHEMBL1494389 | 0.78 | HDAC6 (0.34) | CA1CA2CA7HDAC6HDAC1 | |
| SCHEMBL2027230 | 0.77 | HDAC6 (0.34) | HDAC6HDAC1HDAC2 | |
| SCHEMBL2027231 | 0.77 | HDAC6 (0.34) | HDAC6HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL14966370 | 0.76 | HDAC6 (0.33) | CA1CA2CA7HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736531-A1 | Alpha-substituted pyridazino quinoline compounds | ZENECA LIMITED (GB) | 1996-10-09 | — | — | EP | disclosed |