Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055362 | 0.93 | AGTR1 (0.40) | AGTR1 | |
| SCHEMBL9056223 | 0.89 | AGTR1 (0.43) | AGTR1 | |
| SCHEMBL9042789 | 0.85 | AGTR1 (0.40) | AGTR1 | |
| SCHEMBL9039196 | 0.83 | AGTR1 (0.37) | AGTR1SMN1; SMN2TSHRMAPK1L3MBTL1 | |
| SCHEMBL9041916 | 0.83 | AGTR1 (0.37) | AGTR1TSHR | |
| SCHEMBL9041610 | 0.81 | AGTR1 (0.40) | AGTR1TSHRHPGDHSD17B10 | |
| SCHEMBL9042837 | 0.80 | AGTR1 (0.41) | AGTR1 | |
| SCHEMBL9039137 | 0.80 | AGTR1 (0.44) | AGTR1 | |
| SCHEMBL9041118 | 0.77 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL9055422 | 0.77 | AGTR1 (0.39) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |